1 Table Of Contents 2
1.1 List of Tables 6
1.2 List of Figures 7
2 Executive Summary 8
3 Global Artificial Disc Replacement Market : Market Characterization 9
3.1 Overview 9
3.2 Artificial Disc Replacement Market, Revenue ($m), Historic, 2000 – 2008 10
3.3 Artificial Disc Replacement Market, Revenue ($m), Forecast, 2008 – 2015 11
3.4 Artificial Disc Replacement, Market Dynamics 12
3.4.1 Market Drivers 12
3.4.1.1 Increasing Incidence of Back Pain Will Drive the Artificial Disc Replacement Market 12
3.4.1.2 Availability of New Materials and Methods for Implantation 12
3.4.1.3 Increasing Aging Population and Obesity Driving the Spinal Surgery Market 12
3.4.1.4 Availability of Implants for Younger Patients 13
3.4.1.5 Increasing Adoptability of Minimally Invasive Surgery 13
3.4.2 Market Restraints 13
3.4.2.1 Reimbursement is a Challenge for Artificial Discs 13
3.4.2.2 Alternate Therapies Competing with the Artificial Disc Replacement Market 13
3.4.2.3 Small Patient Segment and Numerous Contraindications Involved with Artificial Disc Replacement Surgery Leading to Low Prescription Rates among Physicians 13
3.4.2.4 Lack of Long-Term Clinical Data Hampering Growth 13
3.4.2.5 Lengthy, Costly and Time-Consuming Approval Process Hindering Growth 14
3.5 Artificial Disc Replacement: Perception Analysis 15
3.6 Artificial Disc Replacement: Opportunities and Unmet Need 16
3.7 Key Takeaway 18
4 Global Artificial Disc Replacement Market : Competitive Assessment 19
4.1 Overview 19
4.2 Strategic Competitor Assessment 19
4.3 Product Profiles of the Major Marketed Products in the Artificial Disc Replacement Market 21
4.3.1 CHARITE Artificial Disc 21
4.3.1.1 Overview 21
4.3.1.2 Efficacy 21
4.3.1.3 Safety Profile 21
4.3.1.4 Pricing 21
4.3.1.5 Clinical Study Details 21
4.3.2 BRYAN Cervical Disc 22
4.3.2.1 Overview 22
4.3.2.2 Efficacy 23
4.3.2.3 Safety 23
4.3.2.4 Pricing 23
4.3.2.5 Clinical study details 23
4.3.3 PRESTIGE Cervical Disc 24
4.3.3.1 Overview 24
4.3.3.2 Efficacy 24
4.3.3.3 Safety 24
4.3.3.4 Pricing 24
4.3.3.5 Clinical study details 24
4.4 Key Take Away 25
5 Global Artificial Disc Replacement Market: Pipeline Assessment 26
5.1 Overview 26
5.2 Strategic Pipeline Assessment 26
5.3 Artificial Disc Replacement – Pipeline by Clinical Phase of Development 29
5.4 Profiles of Promising Devices under Clinical Development 29
5.4.1 Flexicore Lumbar Artificial Disc 29
5.4.1.1 Overview 29
5.4.1.2 Efficacy 29
5.4.1.3 Safety 29
5.4.1.4 Clinical Study Details 30
5.4.2 eDisc 31
5.4.2.1 Overview 31
5.4.2.2 Efficacy 31
5.4.2.3 Safety 31
5.4.2.4 Clinical Study Details 31
5.4.3 DISCOVER Artificial Disc 31
5.4.3.1 Overview 31
5.4.3.2 Efficacy 31
5.4.3.3 Safety 31
5.4.3.4 Clinical Study Details 31
5.5 Artificial Disc Replacement Market: List of Pipeline Products 33
5.6 Key Take Away 34
6 Global Artificial Disc Replacement Market : Implications for Future Market Competition 35
6.1 Strategic Competitor Assessment 36
7 Global Artificial Disc Replacement Market: Emerging Companies 37
7.1 Introduction 37
7.2 Medtronic, Inc. 37
7.2.1 Overview 37
7.2.2 Artificial Disc Replacement Portfolio 37
7.2.2.1 Marketed Products 37
7.2.2.2 Pipeline Products 38
7.3 DePuy 38
7.3.1 Overview 38
7.3.2 Artificial Disc Replacement Portfolio 38
7.3.2.1 Marketed Products 38
7.3.2.2 Pipeline Products 39
7.4 Synthes 39
7.4.1 Overview 39
7.4.2 Artificial Disc Replacement Portfolio 39
7.4.2.1 Marketed Products 39
7.4.2.2 Pipeline Products 39
7.5 Stryker Corporation 40
7.5.1 Overview 40
7.5.2 Artificial Disc Replacement Portfolio 40
7.5.2.1 Marketed Products 40
7.5.2.2 Pipeline Products 40
7.6 Biomet, Inc. 41
7.6.1 Overview 41
7.6.2 Artificial Disc Replacement Portfolio 41
7.6.2.1 Marketed Products 41
7.6.2.2 Pipeline Products 41
8 Appendix 42
8.1 Market Definitions 42
8.1.1 Artificial Disc Replacement 42
8.2 Research Methodology 43
8.3 Secondary Research 44
8.4 Primary Research 44
8.5 Models 45
8.6 Forecasts 45
8.7 Expert Panels 45
8.8 GlobalData Consulting 46
8.9 Contact Us 46
8.10 Disclaimer 461.1 List of Tables
Table 1: Artificial Disc Replacement, Global, Revenue ($m), 2000-2008 10
Table 2: Artificial Disc Replacement, Global, Revenue ($m), 2008-2015 11
Table 3: Safety Results for BRYAN Cervical Disc 23
Table 4: Effectiveness Results for BRYAN Cervical Disc 24
Table 5: Artificial Disc Replacement Pipeline Product Summary 33
Table 6: Medtronic – Marketed Product Summary 37
Table 7: Medtronic – Pipeline Product Summary 38
Table 8: DePuy – Marketed Product Summary 38
Table 9: DePuy – Pipeline Product Summary 39
Table 10: Synthes – Marketed Product Summary 39
Table 11: Synthes – Pipeline Product Summary 40
Table 12: Biomet – Pipeline Product Summary 411.2 List of Figures
Figure 1: Artificial Disc Replacement, Global, Revenue ($m), 2000-2008 10
Figure 2: Artificial Disc Replacement, Global, Revenue ($m), 2008-2015 11
Figure 3: Artificial Disc Replacement: Perception Analysis 15
Figure 4: Artificial Disc Replacement, Opportunity and Unmet Need 17
Figure 5: Strategic Competitive Assessment 20
Figure 6: Technology Trends Analytic Framework 27
Figure 7: Technology Trends Analytic Framework - Descriptions 28
Figure 8: Artificial Disc Replacement – Pipeline by Clinical Phase of Development 29
Figure 9: Strategic Competitor Assessment 36