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Biomarkers in Drug Discovery - Integration in Early Stage Promotes Use of Companion Diagnostics to Optimize Therapeutic Outcomes

2169.71

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Market

Healthcare and Medical

Report Type

Market Research

Country

Global

Published

9 November 2012

Number of Pages

87

Report Delivery

Email

Delivery Lead Time

1-3 hours, 24 hour max

Publisher

GBI Research

File Format

PDF

Global biomarkers market reached value of $13 billion during 2011

The traditional blockbuster model of drug development is coming under fire, as scientists increasingly look towards personalized medicines as the future of pharmaceuticals. Biomarkers are making waves in drug discovery, revealing the possibility of analyzing an individuals medical nature and needs remotely.

According to the Food and Drug Administration (FDA), a biomarker is a characteristic that can be objectively measured and evaluated as an indicator of biologic processes, or as biological responses to a therapeutic treatment, generally existing as specific enzyme or hormone concentrations. The report notes that biomarkers therefore hold the potential to predict disease susceptibility, can detect and monitor disease progression for CNS, CVS, cancer, autoimmune, metabolic and infectious diseases, and can also act as a guiding force in drug development and evaluation.

Historically, drug R&D processes considered the response to a drug on the majority of patients, representing a one-size-fits-all approach, or blockbuster model. Now, an emergence of personalized medicine allows an individuals treatment to be designed according to genetic codes, ensuring a reduction in drug discovery costs and an increase in treatment success.

Promising biomarkers that have already been discovered include biomarkers of neurodegeneration, which correlate better than Aβ biomarkers with the clinical symptoms of Alzheimers Disease (AD) and are better suited for use in clinical trials. A huge number of potential biomarkers of prognosis and diagnosis in Rheumatoid Arthritis (RA) have also been investigated, and autoantibody tests and inflammatory markers are routinely tested in clinical practice. In addition to this, novel, new, non-invasive serum markers are being developed to monitor the progression of Hepatitis C and its response to therapy, in comparison to previously-used liver biopsies.

We have valued the biomarkers market at $3.5 billion in 2004, increasing to $13 billion in 2011 at a Compound Annual Growth Rate (CAGR) of 20.1%. The majority of revenue was generated through the application of biomarkers in the discovery, testing and prescription of oncology therapeutics, according to their analysis, with other leading therapeutics areas being Central Nervous System (CNS) and Cardiovascular System (CVS) disorders.

Report Overview

This report provides information and analysis on the major trends and issues affecting biomarkers in the drug discovery process. The report describes the history of biomarkers and their role in fulfilling the unmet needs of the conventional drug discovery process. The drivers and barriers for the biomarkers market, along with the key issues faced in the application of biomarkers in the drug discovery process, are highlighted. The report discusses some important technologies being used in the discovery and validation of biomarkers.

The integration of different types of biomarkers in each phase of the drug discovery and development process is also studied. Additionally, the report talks about the strategic consolidations that have taken place within the global biomarkers market. These include mergers, acquisitions, and strategic partnerships among companies involved in the manufacturing of biomarkers for drug discovery and research. This report is built using data and information sourced from proprietary databases, primary and secondary research and in-house analysis by GBI Researchs team of industry experts.

This report focuses on the applications of biomarkers in drug development, the market characterization, and promising biomarkers in various therapy areas. Historic and future trends, strategic consolidations and regulatory norms are the other areas discussed in the report.

Scope

- An overview of biomarkers in the drug discovery process along with their use, efficiency and limitations.
- Annualized market data from 2004 and forecast forward to 2018.
- Key market drivers and restraints for the biomarkers market.
- Important technologies being used in the discovery of biomarkers.
- Promising biomarkers that are expected to be used in the drug discovery process in the future.
- The integration of different types of biomarker in each phase of the drug discovery and development process
- Analysis of partnership and M&A deals from 2011 until August 2012.

Reasons to buy

- Develop better strategies for biomarkers research by understanding the market dynamics for the biomarker drug discovery industry.
- Develop market entry and market expansion strategies by identifying the key areas for high growth and opportunities.
- Understand the factors shaping the biomarkers drug discovery market.
- Reinforce the R&D pipeline by identifying the key biomarker tests that can provide more accurate and early diagnosis of diseases.
- Exploit partnership and acquisition opportunities by identifying the products that could fill the portfolio gaps.

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Select License Type

Electronic License

Electronic License

An electronic version (mostly PDF, but can be Excel or PPT), which is either available for immediate download or will be sent via email by the Publisher of the report. The licencing for an electronic version is for use by the purchaser ONLY.

Site License

Site License

An electronic version (mostly PDF, but can be Excel or PPT). Where the report(s) is intended for use by more than one individual, across for example, a site, an office, or a division or country.

Corporate License

Corporate License

An electronic version (mostly PDF, but can be Excel or PPT). Where the report(s) is/are intended for use by an organisation in its entirety. For example, if reports are put on an Intranet or if they are distributed or used by more than one office, division, or country operation, then a Corporate Licence is required.

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