MicroRNA Research Tools, Diagnostics and Therapeutics: Global Markets

Introduction

Study Goals And Objectives
Reasons For Doing This Study
Scope And Format
Methodology And Information Sources
Intended Audience
Analyst Credentials
Related Reports
Bcc On-Line Services
Disclaimer

Summary

Summary Table Global Market For MicroRNA Research Tools, Diagnostic And Therapeutic Products, Through 2017 ($ Millions)
Summary Figure Global Market For MicroRNA Research Tools, Diagnostic And Therapeutic Products, 2010-2017 ($ Millions)

Introduction To MicroRNA Research

Overview
MicroRNA Discovery
MicroRNA Definition
Biogenesis Of MicroRNA
Figure 1 Schematic Representation Of MicroRNA Biogenesis And Its Effect On Protein Translation
Function Of MicroRNA
MicroRNA Market Overview
Tools For Research Of MicroRNA Molecules
Table 1 Global Market For Reagents And Tools For Dna/Rna Research, Through 2016 ($ Billions)
MicroRNA As Biomarker And Its Role In Bioprofiling And Diagnostics Products Development
Table 2 Market For Cancer Profiling Technologies, Through 2015 ($ Billions)
MicroRNA As Therapeutics Target In Drug Discovery
Importance Of Patents In MicroRNA Research
Table 3 Patents And Patent Application Search In MicroRNA Research Using Specific Key Words, Through 2012
Mir-34 Example
Mir-122 Case
Table 4 Number Of Patents And Patent Applications In MicroRNA Research According To Assignee

Research Tools And Reagents For MicroRNA Research And Product Development

Overview
Table 5 Types Of Reagents And Tools For MicroRNA Research And Drug Discovery And Their Relative Market Share, 2011 (%)
Table 6 Examples Of MicroRNA Sample Preparation Services And Their Price Ranges ($)
Analysis Of Main Sectors In The MicroRNA Research Tools And Technologies Market
Qrt-Pcr And Related Reagents For MicroRNA Research
Rna Extraction And Purification Products
Table 7 Global Market Shares Of Rna Isolation Products By Company (%)
Formalin Fixed Paraffin-Embedded Tissues As A Source For MicroRNA
Qrt-Pcr Procedure For MicroRNA Analysis
Table 8 Global Rt-Pcr Market Shares By Company, 2011 (%)
Table 9 Platforms And Vendors Of Qrt-Pcr Producst For MicroRNA Research
Table 10 Global Market For Qrt-Pcr Reagents For MicroRNA Research, Through 2017 ($ Millions)
Microarrays As A Tool For Research And Product Development For MicroRNA Diagnostics And Therapeutics
Table 11 Main Representative Microarray Products For MicroRNA Research
Table 12 Annual Revenues Of Affymetrix, 2009-2011 ($ Millions)
Table 13 Global Market For Microarray Reagents And Products For MicroRNA Research, Through 2017 ($ Millions)
MicroRNA Sequencing As A Tool For MicroRNA Research, Diagnostics And Drug Discovery
Ngs Platforms For Mirnaseq
Table 14 Global Market For Ngs Sequencing, Through 2016 ($ Billions)
Table 15 Ngs Market Share By Company, 2011 (%)
Table 16 Platforms And Vendors Used For MicroRNA Sequencing
Sample Preparation For MicroRNA Sequencing
Table 17 Value Of Global Ngs Sample Prep Market, Through 2016 ($ Millions)
Summary And Comparison Of MicroRNA Profiling Techniques
Table 18 Summary Of MicroRNA Profiling Techniques Advantages And Disadvantages
Functional Assay For MicroRNA Research
Table 19 Examples Of Products For Functional Assays And Their Representative Vendors
Summary Of Life Science Tools And Reagents Market For MicroRNA Research
Table 20 Global Market For Research Tools In MicroRNA Research, Through-2017 ($ Millions)
Figure 2 Global Market For Research Tools In MicroRNA Research, 2010-2017 ($ Millions)

MicroRNA Diagnostics And Biomarker Market

Overview
Table 21 Number Of Publications In MicroRNA Research Based On Different Search Criteria
MicroRNA And Cancer Diagnostics
Table 22 Examples Of Differentially Expressed MicroRNA In Different Cancer Types
Importance Of MicroRNA Signatures In Different Diseases
Table 23 Examples Of MicroRNA Expression In Cvs Conditions
Table 24 Examples Of MicroRNA Downregulated Or Upregulated In Different Neurodegenerative Pathologies
Current State Of MicroRNA Diagnostic And Biomarker Product Development Market
Table 25 Global Biomarkers Market, Through 2015 ($ Billions)
Table 26 Challenges Associated With MicroRNA Measurements As Biomarker
Current Diagnostic MicroRNA Products And Pipelines
Table 27 Diagnostics Products By Rosetta Genomics
Mirview Lung Test
Mirview Meso Test
Mirview Kidney Test
Mirview Mets
Rosetta Genomics
Table 28 Revenues For Rosetta Genomics, 2009-2011 ($ Millions)
Table 29 Global MicroRNA Diagnostics Market Through 2017 ($ Millions)
Figure 3 Global MicroRNA Diagnostics Market, 2010-2017 ($ Millions)
Bioprofiling Services As A Positive Drive For Diagnostics Industry
Table 30 Example Of Exiqon Revenues, 2009-2012 ($ Millions)

MicroRNA Therapeutics In Rna Drug Discovery Market

Overview
Rna Therapeutics
Antisense Oligonucleotide Approach
Mechanisms Of Action Of Antisense Oligonucleotides
Antisense Drugs As A Proof Of Concept
Table 31 Example Of Lipitor Sales As An Estimate For Kynamro, 2008-2010 ($ Billions)
Table 32 Examples For Isis Pharmaceuticals Revenues, 2009-2011 ($ Millions)
Rna Interference As Drug Discovery Platform
Mechanism Of Action For Rna Interference (Rnai)
Rnai As Therapeutics Approach
Table 33 Revenues Of Alnylam Pharmaceuticals And Tekmira Pharmaceuticals, 2009-2011 ($ Millions)
Ribozymes Approach For Rna Based Therapeutics
Market Evaluation For Antisense And Rnai Based Drugs
Table 34 Examples Of Drug Candidates In Antisense And Rna Interference Based Approaches
Table 35 Global Market For Antisense Drug Discovery Through 2017 ($ Millions)
Table 36 Examples Of Deals And Collaboration In Rnai Therapeutics, 2009-2012
Table 37 Global Market For Rnai Therapeutic Approach, Through 2017 ($ Millions)
MicroRNA Approach In Drug Discovery
Table 38 Examples Of MicroRNA Differential Expression In Different Cellular Processes
Stability Aspects And Chemical Modification
"Decoy" Transcripts: Competition For Endogenous MicroRNAs
MicroRNA Replacement Therapy As Therapeutic Approach
MicroRNA Regulation As A Tool For Traditional Gene Therapy Approach
Table 39 Different Approaches For Development Of MicroRNA Based Therapeutics
Delivery Aspects Of MicroRNA And Rna Based Therapeutics
Table 40 Global Market For Rna Drug Delivery, Through 2017 ($ Billions)
Table 41 Main Approaches And Techniques In Nonviral Rna Drug Delivery
Table 42 Rna Drug Delivery Systems By Company
Table 43 Summary Of Main Drug Development Platforms For MicroRNA Therapeutics: Limitations And Advantages
Evaluation Of MicroRNA Drug Discovery Market And Its Participants
Table 44 Main Market Participants In MicroRNA Drug Discovery And Examples Of Their Drug Candidates
Santaris Pharma
Table 45 Sales Of Incivek And Victrelis, 2011 And 2012 ($ Millions)
Miragen
Regulus Therapeutics
Drug Development For Fibrosis Treatment
Anti-Hepatitis C Virus Drug Development
Immune System Related Diseases
Metabolic Diseases Drug Development
Development Of MicroRNA Therapeutics For Oncology Market
Rosetta Genomics
Mirna Therapeutics
Interna Technologies
Additional Drug Discovery Companies
Table 46 Revenues For Santaris Pharma And Regulus Therapeutics, 2008-2011 ($ Millions)
Table 47 Recent Collaborations, Deals And Agreements In The MicroRNA Drug Discovery Market, 2008-2012
Table 48 Global Market For MicroRNA Drug Discovery Through 2017 ($ Millions)
Figure 4 Global Market For MicroRNA Drug Discovery 2010-2017 ($ Millions)
Development Of Additional Sub Markets In MicroRNA Drug Discovery Market
Sistemic
Cenix Bioscience Cro
Pyxant Labs
Polyplus Transfection
Accelero Bioanalytics
Summary Of General Rna Therapeutics Drug Discovery Market
Table 49 Global Market For Rna-Based Therapeutics, Through 2017 ($ Millions)
Figure 5 Global Market For Rna Based Therapeutics, 2010-2017 ($ Millions)
Table 50 Geographical Distribution Of Rna-Based Drug Discovery Companies (%)

Importance Of Bioinformatics Tools And Recourses For MicroRNA

Research And Product Development
Overview
Table 51 Global Bioinformatics Market, Through 2016 ($ Billions)
Table 52 Databases For MicroRNA Research
Table 53 Examples Of Computational Tools For MicroRNA Prediction And Target Identification
Effect Of Ngs Trend On MicroRNA Research And Bioinformatics Tool Development

New Technologies, Applications And Markets In MicroRNA Research

And Product Development
New Technologies And Drug Discovery Approaches
Table 54 Protein Targets For Drug Discovery Research In MicroRNA
New Applications And Target Markets In MicroRNA Research
Agricultural Market For MicroRNA
Biofuel Market For MicroRNA
Table 55 Global Market For Biofuels, Through 2017 ($ Billions)
Livestock Market For MicroRNA
Forensics As A Target Market In MicroRNA Research And Development

Market Summary For MicroRNA Research And Product Development

Table 56 Global Market For MicroRNA Research Tools, Diagnostic And Therapeutic Products, Through 2017 ($ Millions)
Figure 6 Global Market For MicroRNA Research Tools, Diagnostic And Therapeutic Products, 2010-2017 ($ Millions)
Table 57 Main Market Participants In MicroRNA Research Market

Profiles Of Select Companies

Alnylam Pharmaceuticals
Asuragen, Inc.
Exiqon A/S
Isis Pharmaceuticals
Mirna Therapeutics
Regulus Therapeutics
Rosetta Genomics
Santaris Pharma A/S

List Of Companies Mentioned In Report

Access Pharmaceuticals
Aegera Therapeutics
Affymetrix
Agilent Technologies
Alnylam Pharmaceuticals
Antisense Pharma Gmbh
Aparna Biosciences Corp.
Applied Biological Materials Inc.
Astrazeneca Pharmaceuticals Lp
Asuragen Inc.
Avi Biopharma/Sarepta Therapeutics
Benitec Biopharma
Biocancell Therapeutics Inc.
Biogen Idec
Calando Pharmaceuticals Inc.
Cbc Comprehensive Biomarker Center Gmbh
Cenix Bioscience Gmbh
Clontech Laboratories
Covance Inc.
Dicerna Pharmaceuticals Inc.
Egen Inc.
Eli Lilly And Co.
Emd4biosciences
Enzo Biochem
Enzon Pharmaceuticals Inc.
Exiqon A/S
F. Hoffman-La Roche Ag
Fluidigm
Genecopoeia Inc.
Genosensor Corp.
Gensignia Inc.
Genta Inc.
Groove Biopharma
Gsk U.S.
Htg Molecular Diagnostics Inc.
Ico Therapeutics Inc.
Idera Pharmaceuticals
Illumina Inc.
Inovio
Interna Technologies B.V.
Isis Pharmaceuticals
Lc Sciences
Life Technologies Corp.
Lorus Therapeutics Inc.
Marina Biotech
Merck
Miragen Therapeutics
Mirna Therapeutics
Nanostring Technologies
Norgen Biotek
Novartis International Ag
Opko Health Inc.
Pfizer
Phalanx Biotech Group
Phaserx
Prolias Technologies
Qiagen
Quark Pharmaceuticals Inc.
Regulus Therapeutics
Rosetta Genomics
Rxi Pharmaceuticals Corp.
Sanofi U.S.
Santaris Pharma A/S
Senesco Technologies Inc.
Sigma-Aldrich
Silence Therapeutics
Sirnaomics Inc.
Sirnasense
Sylentis
Tacere Therapeutics Inc.
Tekmira Pharmaceuticals Corp.
Theradiag
Thermo Fisher Scientific Inc.
Traversa Therapeutics Inc.
Wafergen Biosystems Inc.

List of Tables

Summary Table Global Market For MicroRNA Research Tools, Diagnostic And Therapeutic Products, Through 2017 ($ Millions)
Table 1 Global Market For Reagents And Tools For Dna/Rna Research, Through 2016 ($ Billions)
Table 2 Market For Cancer Profiling Technologies, Through 2015 ($ Billions)
Table 3 Patents And Patent Application Search In MicroRNA Research Using Specific Key Words, Through 2012
Table 4 Number Of Patents And Patent Applications In MicroRNA Research According To Assignee
Table 5 Types Of Reagents And Tools For MicroRNA Research And Drug Discovery And Their Relative Market Share, 2011 (%)
Table 6 Examples Of MicroRNA Sample Preparation Services And Their Price Ranges ($)
Table 7 Global Market Shares Of Rna Isolation Products By Company (%)
Table 8 Global Rt-Pcr Market Shares By Company, 2011 (%)
Table 9 Platforms And Vendors Of Qrt-Pcr Producst For MicroRNA Research
Table 10 Global Market For Qrt-Pcr Reagents For MicroRNA Research, Through 2017 ($ Millions)
Table 11 Main Representative Microarray Products For MicroRNA Research
Table 12 Annual Revenues Of Affymetrix, 2009-2011 ($ Millions)
Table 13 Global Market For Microarray Reagents And Products For MicroRNA Research, Through 2017 ($ Millions)
Table 14 Global Market For Ngs Sequencing, Through 2016 ($ Billions)
Table 15 Ngs Market Share By Company, 2011 (%)
Table 16 Platforms And Vendors Used For MicroRNA Sequencing
Table 17 Value Of Global Ngs Sample Prep Market, Through 2016 ($ Millions)
Table 18 Summary Of MicroRNA Profiling Techniques Advantages And Disadvantages
Table 19 Examples Of Products For Functional Assays And Their
Representative Vendors
Table 20 Global Market For Research Tools In MicroRNA Research, Through-2017 ($ Millions)
Table 21 Number Of Publications In MicroRNA Research Based On Different Search Criteria
Table 22 Examples Of Differentially Expressed MicroRNA In Different Cancer Types
Table 23 Examples Of MicroRNA Expression In Cvs Conditions
Table 24 Examples Of MicroRNA Downregulated Or Upregulated In Different Neurodegenerative Pathologies
Table 25 Global Biomarkers Market, Through 2015 ($ Billions)
Table 26 Challenges Associated With MicroRNA Measurements As Biomarker
Table 27 Diagnostics Products By Rosetta Genomics
Table 28 Revenues For Rosetta Genomics, 2009-2011 ($ Millions)
Table 29 Global MicroRNA Diagnostics Market Through 2017 ($ Millions)
Table 30 Example Of Exiqon Revenues, 2009-2012 ($ Millions)
Table 31 Example Of Lipitor Sales As An Estimate For Kynamro, 2008-2010 ($ Billions)
Table 32 Examples For Isis Pharmaceuticals Revenues, 2009-2011 ($ Millions)
Table 33 Revenues Of Alnylam Pharmaceuticals And Tekmira Pharmaceuticals, 2009-2011 ($ Millions)
Table 34 Examples Of Drug Candidates In Antisense And Rna Interference Based Approaches
Table 35 Global Market For Antisense Drug Discovery Through 2017 ($ Millions)
Table 36 Examples Of Deals And Collaboration In Rnai Therapeutics, 2009-2012
Table 37 Global Market For Rnai Therapeutic Approach, Through 2017 ($ Millions)
Table 38 Examples Of MicroRNA Differential Expression In Different Cellular Processes
Table 39 Different Approaches For Development Of MicroRNA Based Therapeutics
Table 40 Global Market For Rna Drug Delivery, Through 2017 ($ Billions)
Table 41 Main Approaches And Techniques In Nonviral Rna Drug Delivery
Table 42 Rna Drug Delivery Systems By Company
Table 43 Summary Of Main Drug Development Platforms For MicroRNA Therapeutics: Limitations And Advantages
Table 44 Main Market Participants In MicroRNA Drug Discovery And Examples Of Their Drug Candidates
Table 45 Sales Of Incivek And Victrelis, 2011 And 2012 ($ Millions)
Table 46 Revenues For Santaris Pharma And Regulus Therapeutics, 2008-2011 ($ Millions)
Table 47 Recent Collaborations, Deals And Agreements In The MicroRNA Drug
Discovery Market, 2008-2012
Table 48 Global Market For MicroRNA Drug Discovery Through 2017 ($ Millions)
Table 49 Global Market For Rna-Based Therapeutics, Through 2017 ($ Millions)
Table 50 Geographical Distribution Of Rna-Based Drug Discovery Companies (%)
Table 51 Global Bioinformatics Market, Through 2016 ($ Billions)
Table 52 Databases For MicroRNA Research
Table 53 Examples Of Computational Tools For MicroRNA Prediction And Target Identification
Table 54 Protein Targets For Drug Discovery Research In MicroRNA
Table 55 Global Market For Biofuels, Through 2017 ($ Billions)
Table 56 Global Market For MicroRNA Research Tools, Diagnostic And Therapeutic Products, Through 2017 ($ Millions)
Table 57 Main Market Participants In MicroRNA Research Market

List of Figures

Summary Figure Global Market For MicroRNA Research Tools, Diagnostic And Therapeutic Products, 2010-2017 ($ Millions)
Figure 1 Schematic Representation Of MicroRNA Biogenesis And Its Effect On Protein Translation
Figure 2 Global Market For Research Tools In MicroRNA Research, 2010-2017 ($ Millions)
Figure 3 Global MicroRNA Diagnostics Market, 2010-2017 ($ Millions)
Figure 4 Global Market For MicroRNA Drug Discovery 2010-2017 ($ Millions)
Figure 5 Global Market For Rna Based Therapeutics, 2010-2017 ($ Millions)
Figure 6 Global Market For MicroRNA Research Tools, Diagnostic And Therapeutic Products, 2010-2017 ($ Millions)