1 Table of Contents 3
1.1 List of Tables 5
1.2 List of Figures 6
2 Introduction 7
2.1 Report Guidance 7
3 Market Overview 9
3.1 Stem Cell Research – An Introduction 9
3.2 Types of Stem Cell Research 9
3.3 Unmet Needs 10
3.4 Applications of Stem Cell Research 14
4 Market Characterization 16
4.1 Stem Cell Market – An Introduction 16
4.2 Market Sizing 16
4.3 Therapy cost 18
4.4 Technology Adoption Framework 19
4.5 Types of Business Models 19
4.6 Market Drivers 21
4.6.1 Supporting Political Environment on Embryonic Stem Cell Research will Advance the Stem Cell Industry to Prosper in the United States 21
4.6.2 Limited Availability of Treatments to Treat Certain Disease Conditions Increases Market Opportunity for Stem Cell Research 22
4.7 Market Barriers & Challenges 23
4.7.1 Stem Cell Research and Development is an expensive process which requires considerable funding to be operational. 23
4.7.2 Availability of Adequate Reimbursements are Unclear and leads to a conundrum 23
4.7.3 Ethical, legal and social issues persists and acts as a challenge 24
4.7.4 Identifying, recruiting and retaining the best scientific talents is an intractable process for stem cell research based companies 25
4.8 Stem Cell Research and Development - Market Trends 25
4.8.1 Booming Stem Cell Tourism is a Potential Opportunity for Countries to Attract Investments. 25
4.8.2 ASLAP Analysis of Stem Cell Tourism 26
4.8.3 Federal Funding Support Improves the Stem Cell Research Environment 27
4.8.4 Increasing Entry of Pharmaceutical Companies Boosts Stem Cell Research & Development 28
4.8.5 PESTLE Analysis 30
4.8.6 SWOT Analysis of Stem Cell Research & Development 31
4.9 Industry Analysis 33
5 Stem Cell Research and Development - Pipeline Analysis 35
5.1 Pipeline by Various Phases 35
5.2 Phase III Pipeline Analysis 35
5.3 Phase II Pipeline Analysis 37
5.4 Preclinical and Phase 1 Pipeline 39
6 Stem Cell Research and Development - Investment Trends 40
6.1 Investor’s Perspective on Stem Cell Research 40
6.2 NIH spending in Stem Cell Research and Development is Increasing and is Supportive 42
6.2.1 NIH Spending by Stem Cell Research Type 43
6.2.2 High Budget Projects Funded by NIH 44
6.3 States Funding on Stem Cell Research in the US is in Reconsideration. 45
6.4 R&D Spending by Stem Cell Research Companies 46
7 Stem Cell Research and Development - Geographical Trends 47
7.1 Stem Cell Companies by Geographic Regions 47
7.2 The United States 48
7.3 United Kingdom 49
7.4 China 50
7.5 Netherlands 51
7.6 Singapore 52
7.7 South Korea 53
7.8 Japan 54
7.9 India 55
7.10 Sweden 56
7.11 Denmark 57
7.12 France 58
7.13 Germany 59
7.14 Israel 60
7.15 Australia 61
7.16 Canada 62
7.17 Czech Republic 63
8 Stem Cell Research and Development - Mergers and Acquisitions 64
9 Stem Cell Research and Development - Competitive Structure 65
9.1 Stem Cell Companies by Therapy Areas 65
9.2 Stem Cell Companies by Stem Cell Types 66
10 Stem Cell Research and Development - Company Profiles 67
10.1 Aastrom Biosciences 67
10.2 Osiris Therapeutics 67
10.3 Bioheart 68
10.4 Aldagen 68
10.5 Mesoblast 69
10.6 Geron 69
10.7 Advanced Cell Technology 70
10.8 Cytori Therapeutics 70
10.9 Pluristem Therapeutics 71
10.10 Medistem 71
10.11 Neostem 72
11 Stem Cell Research and Development - Conclusion 73
12 Appendix 74
12.1 Market Definitions 74
12.2 Key Support Data 74
12.3 Abbreviations 74
12.4 Methodology 74
12.4.1 Coverage 75
12.4.2 Secondary Research 75
12.4.3 Primary Research 76
12.4.4 Expert Panels 76
12.5 Contact Us 76
12.6 Disclaimer 761.1 List of Tables
Table 1: Disease Conditions and Population in US 18
Table 2: Preferred Countries for Stem Cell Tourism 25
Table 3: Pharmaceutical Companies Partnership Environment 29
Table 4: Phase III Pipeline 35
Table 5: Phase II Pipeline 37
Table 6: Preclinical and Phase 1 Pipelines 39
Table 7: NIH Spending 42
Table 8: Spending of States in US on Stem Cell Research 45
Table 9: Mergers and Acquisitions in Stem Cell Research 64
Table 10: Aastrom Biosciences 67
Table 11: Osiris Therapeutics 67
Table 12: BioHeart 68
Table 13: Aldagen 68
Table 14: Mesoblast 69
Table 15: Geron 69
Table 16: Advanced Cell Technology 70
Table 17: Cytori Therapeutics 70
Table 18: Pluristem Therapeutics 71
Table 19: Medistem 71
Table 20: Neostem 721.2 List of Figures
Figure 1: Stem Cell Research and Development Segmentation 9
Figure 2: Stem Cells – Interaction Framework 11
Figure 3: Cells Models –Present and the Future 12
Figure 4: Unmet Need Vs Time to Market 13
Figure 5: Adult Stem Cells – Applications 14
Figure 6: Technology Adoption Framework 19
Figure 7: Business Models in Stem Cell Industry 20
Figure 8: Political Environnent – Impact Analysis 21
Figure 9: Treatment Availability – Impact Analysis 22
Figure 10: Cost of Research – Impact Analysis 23
Figure 11: Reimbursements – Impact Analysis 23
Figure 12: Ethical, legal and Social Issues – Impact Analysis 24
Figure 13: Human Resources – Impact Analysis 25
Figure 14: ASLAP Analysis of Stem Cell Tourism 26
Figure 15: Stem Cell Research- Federal Funding Trend 27
Figure 16: PESTLE Analysis of Stem Cell Research 30
Figure 17: SWOT Analysis of Stem Cell Research and Development 31
Figure 18: SWOT Analysis of Stem Cell Research and Development – Impact Grid 32
Figure 19: Five Force Analysis 33
Figure 20: Stem Cell Development Pipeline by Clinical Trial Phase 35
Figure 21: VC’s Perspective on Stem Cell Research 40
Figure 22: VC’s Perspective on Stem Cell Research – Impact Analysis 41
Figure 23: NIH Spending by Stem cell Research Type 43
Figure 24: High Budget Projects Funded by NIH 44
Figure 25: R&D Spending by Public Companies 46
Figure 26: Stem Cell Companies by Geographic Regions 47
Figure 27: Country Analysis – United States 48
Figure 28: Country Analysis – United Kingdom 49
Figure 29: Country Analysis – China 50
Figure 30: Country Analysis – Netherlands 51
Figure 31: Country Analysis – Singapore 52
Figure 32: Country Analysis – South Korea 53
Figure 33: Country Analysis – Japan 54
Figure 34: Country Analysis – India 55
Figure 35: Country Analysis – Sweden 56
Figure 36: Country Analysis – Denmark 57
Figure 37: Country Analysis – France 58
Figure 38: Country Analysis – Germany 59
Figure 39: Country Analysis – Israel 60
Figure 40: Country Analysis – Australia 61
Figure 41: Country Analysis – Canada 62
Figure 42: Country Analysis – Czech Republic 63
Figure 43: Mergers and Acquisitions – Year wise Analysis 64
Figure 44: Stem Cell Companies by Therapy Areas 65
Figure 45: Stem Cell Companies by Stem Cell Types 66
Figure 46: Methodology 75