Contract Research Outsourcing (CRO) - A Global Update of Market Trends & Opportunities

1.METHODOLOGY
Study Reliability and Reporting Limitations
Disclaimers
Quantitative Techniques & Reporting Level
2.INDUSTRY OVERVIEW
Background
Growth and Transformation of CRO Industry
Advantages of CRO for Pharma and Biotech Companies
Advantages of CRO for Clinical Research Organizations
3.INDUSTRY POTENTIAL
Outlook
Competition Potential
Regional Potential
The United States
Western Europe
Central and Eastern Europe
Asia-Pacific
China
India
Latin America
Service Potential
Pre-Clinical Segment Gains Momentum
Clinical Research – Encouraging Factors at Various Phases
Phase I
Phase II
Phase III
Phase IV
Research & Development Potential
4.MARKET DYNAMICS
Challenges Faced by Contract Research Organizations
On-shore versus Offshore CRO Business
Cutthroat Competition Among CROs
Management of Production Capacities
Management of Clinical Investigation
Cost Containment
Safety Concerns on Clinical Trials
Pipeline Blocks
Strategies and Tactical Programs for CROs
Survival Strategies in Mature CRO Markets
Exit from the Industry
Expand Scale
Capture Niche Segments
Expand Geographically
Strategies to Tap Opportunities in Growing Markets
Mobilize Funds
Expand Other Services
Upgrade Technological and Knowledge Base
Form Sub-Contracts or Regional Alliances
Asia – Hub for Contract Research Outsourcing
Overview
Market Potential
Activity Perspective
Cost-Efficiency in Research and Development
World-Class Clinical Trials
Regional Perspective
China
Congenial Business Environment
Compliance with Global CRO Standards
Return of Skilled Human Resources
Availability of Large Genetic Population
Cost Advantages
India
Large Talent Pool of Human Resources
Increased Regulatory Compliance
Rich Genetic Diversity
Cost-Savings and World-Class Quality
Challenges in Outsourcing
China
Regulatory Hurdles
Limited Funding Resources
Demand War for Talented Personnel
Teething problems
Cultural and Language Difficulties
India
Restrictions on Clinical Trials
Lack of Standardization
Advantage India – hot spot for R&D investment
Subject-compliance in major therapeutic areas
Reliable Data Generation and Management
Improved Base of Medical Infrastructure
Strong Combination of CMOs and CROs
Reverse-engineering Capabilities
Market Trends
Biotech Leads in CRO
5.CORPORATE DEVELOPMENTS
Symyx Takes Over Integrity Biosolution
Worldwide Clinical Trials Acquires MediQuest
BioImagene Launches a New CRO, AgilityBio
Tigermed Receives Investments from Qiming
Covance Inks MoU with WuXi for a Chinese Joint Venture
Veeda Takes Over International Oncology Network
Kendle Acquires DecisionLine
Encorium to Take Over Prologue Research
PharmaLinkFHI Takes Over Matrix Contract Research Ltd.
Encorium Receives Business Contracts for North America and Europe
India’s Jubilant Organosys to Takeover Draxis Health
Shasun to Establish Process Development Unit in US
Quintiles to Open Second Clinical Research Office in Wilmington
LabCorp to Acquire Tandem Labs
Shasun to Establish Process Development Unit in US
MDS Pharma Expands in Latin America
Iris Pharma and Clirophtha Merge to form New Iris Pharma
PPD to Acquire InnoPharm
KCR Acquires DUX Consuling
Cetero Research Acquires DGD Research
Jubilant Organosys Acquires Hollister-Stier Laboratories
Shasun Acquires Rhodia Pharma Plants
Ocimum Biosolutions Acquires Gene Logic’s Genomics Business
Innovative Medical Device Sourcing Acquires Frontier BioMedical LLC
UK-Based Premier Research Group PLC Acquires ARS, Inc.
AAIPharma, Inc. Acquires Instituto de Pesquisa Clínica de São Paulo Ltda
Covance to Renovate New Drug Development Facility in Virginia
Covance Expands and Reshuffles Research Clinic
Perceptive Informatics Alliance To Enhance Clinical Supply Chain Forecasting and Management
Genstar Capital Acquires PRA International
Covalent Acquires Remedium Oy and Changes Name to Encorium
Quintiles Enters Into a New Alliance with Washington County Hospital
Kendle Expands in US and Europe
Criterium Opens Two New Offices in Russia and Israel
Premier Research Acquires Two Companies to Expand Product Offerings
Averion Divests Staffing Services Segment
Chiltern Acquires CTMS
Quintiles Acquires Bio-Trials
Parexel Acquires Apex International Clinical Research
Charles River Forms Joint Venture with BioExplorer
PAREXEL Opens New Location In India
Avesthagen and Manipal Accunova Collaborate
Matrix and ethica Clinical Research form ethicamatrix
Covance Opens Nutritional Chemistry Laboratory in Singapore
MDS Pharma to Expand in European Market
Vita Nova Acquires Sedoc
Averion Acquires Hesperion
Averion and BIOCANCER Form Strategic Alliance
AstraZeneca Opens First CPU to Enhance Clinical Research in China
AstraZeneca Acquires Biologics Manufacturing Facility
AstraZeneca Inaugurates Global Process R&D Lab in Bangalore
6.MAJOR PLAYERS
Contract Research Organizations
Criterium, Inc. (US)
Covance, Inc. (US)
Encorium Group, Inc. (US)
ICON PLC (Ireland)
Kendle (US)
Life Sciences Research, Inc. (US)
MDS Pharma Services (US)
MPI Research (US)
Omnicare Clinical Research (US)
Parexel International Corporation (US)
PharmaNet Development Group, Inc. (US)
PRA International (US)
Pharmaceutical Product Development, Inc. (US)
Quintiles Transnational Corporation (US)
WIL Research Laboratories, LLC (US)
Preclinical Laboratories
Bio Analytical Research Corporation (US)
Calvert Laboratories, Inc. (US)
CentraLabS Clinical Research (US)
Charles River Laboratories, Inc. (US)
Huntingdon Life Sciences Research, Inc. (UK)
Laboratory Corporation of America® Holdings (US)
Lab Research, Inc. (Canada)
Pacific Biometrics, Inc. (US)
Perry Scientific, Inc. (US)
Quest Diagnostics, Inc. (US)
SNBL USA, Ltd. (US)
Site Management Organizations
DaVita Clinical Research (US)
nTouch Research Corporation (US)
PharmaTrials, Inc. (US)
Radiant Research, Inc. (US)
Research Solutions, LLC (US)
7.MARKET ANALYTICS
8.THE UNITED STATES
Market Overview
Competitive Scenario
9.EUROPE
Market Overview and Outlook
Competitive Scenario
Eastern Europe – Center for Clinical Trials
10.ASIA
Promising Market
Outsourcing Destinations: China and India
Promoting Role of the Government
Focus on Key Markets
India
A Thriving Clinical Trial Market
Reasons for Outsourcing to India
List of Pharmaceutical Companies Outsourcing Clinical Research to India
SWOT Analysis
Competitive Scenario
Regulatory Environment
China
Factors Favoring Outsourcing Activity
SWOT Analysis
Policies Governing Clinical Trials
Clinical Research Market Size
11.REST OF WORLD
Exhibits
Table 1: Percentage Breakdown of Pipeline Drugs by Phase in the World -
Table 2: Percentage Breakup of Life Sciences Revenues of Major Players by Service Type -
Table 3: Number of CROs by Service Type in the World -
Table 4: Market Shares of Pre-clinical CRO Providers in the World -
Table 5: Leading Biotechnology and Pharmaceutical Research Companies Worldwide – Ranked by Year 2006 Revenues in US$ Million
Table 6: Percentage Breakup of Global R&D Spending by Region (2008E)
Table 7: Percentage Breakup of Global R&D Spending by Market (2007-2010)
Table 8: Cost of Conducting Clinical Trials: India Vs US (In US$ Million)
Table 9: Global Contract Research Outsourcing by Region for the Period 2007-2015 (Sales in US$ Million)
Table 10: Percentage Breakdown of Global Contract Research Outsourcing by Region for the Years 2008 & 2009
Table 11: Global Contract Research Outsourcing for Drug Discovery by Region for the Period 2007-2015 (Sales in US$ Million)
Table 12: Percentage Breakdown of Global Contract Research Outsourcing for Drug Discovery by Region for the Years 2008 & 2009
Table 13: Global Contract Research Outsourcing for Clinical Research by Region for the Period 2007-2015 (Sales in US$ Million)
Table 14: Percentage Breakdown of Global Contract Research Outsourcing for Clinical Research by Region for the Years 2008 & 2009
Table 15: Percentage Breakdown of CRO Revenues by Player Category -
Table 16: Contract Research Outsourcing by Service Segment in the US: 2007-2015 (Sales in US$ Million)
Table 17: Percentage Breakdown of Contract Research Outsourcing by Service Segment in the US for the Years 2008 & 2009
Table 18: Contract Research Outsourcing by Service Segment in Europe: 2007-2015 (Sales in US$ Million)
Table 19: Percentage Breakdown of Contract Research Outsourcing by Service Segment in Europe for the Years 2008 & 2009
Table 20: CRO Market Size (US$ million) for Clinical Research in Asia (2007-08)
Table 21: Indian CRO Market Revenues in US$ Million (2007-2010)
Table 22: CRO Market Size (US$ million) for Clinical Research in China (2007-08)
Table 23: Percentage Breakdown of Japanese CRO Value Sales by Segment -
Table 24: Contract Research Outsourcing by Service Segment in Asia: 2007-2015 (Sales in US$ Million)
Table 25: Percentage Breakdown of Contract Research Outsourcing by Service Segment in Asia for the Years 2008 & 2009
Table 26: Contract Research Outsourcing by Service Segment in Rest of World: 2007-2015 (Sales in US$ Million)
Table 27: Percentage Breakdown of Contract Research Outsourcing by Service Segment in Rest of World for the Years 2008 & 2009
Companies Profiled